they are the proteins in the blood aka antibodies. they are obviously work constantly physiologically in order to protect us from pathogens. they are produced by modified B cells ( plasma cells) in different phases of the immune reaction and have a unique structure that can very selectively interact with antigens, C components and other cells of the immune system to neutralize the pathogen. M type are produced acutely and G type follows by maturation of the immune response and alternative splicing.. A type usually resides in the skin and mucus membranes and appears in dimers. E type released from mast cells and basophils in allergic reactions.
they can be administered clinically in case of massive, life threatening infection to which there is no immune memory until the body recovers and can produced its own gammaglobulins. there presence in immune assays is a marker of exposure to or vaccination state from a pathogen of interest.
